5-MeO-MiPT also known as 5-Methoxy-N-methyl-N-isopropyltryptamine or Moxy is one of the most famous psychedelics of the tryptamine class. 5-MeO-MiPT is closely related to the other tryptamines like 5-MeO-DMT and 5-MeO-DiPT and produces psychoactive effects by acting on our serotonin receptors and tricking our brain into releasing more serotonin and dopamine giving the feeling of happiness, inducing flow state and all the other effects that can be classified as “having a trip”. The first-ever Moxy chemical was created by accident and from that point forward there has been a whole mystery about how these accidentally synthesized research chemicals affect our serotonin receptors. The research that has been done on this research chemical is not enough to rule out the possibilities of extensive use but also retains the possibility of problems like permanent nerve damage and changes in the physical structure of the brain. The synthesis of 5-MEO-MiPT was first done in 1985 by David Repke along with the infamous writer of the book TiHKAL (“Tryptamines I Have Known and Loved”), Alexander Shulgin. The earliest human clinical trials were done by both of them and they have reported by a single report of their research in the book.
5-MeO-MiPT has been reported to induce highly stimulating visual distortions which create the illusions of seeing paranormal things or losing our sense of to interpret depth also known as 3D depravity. There have been reports of stronger tactile responses among a large number of cases over varying doses of the chemical and reports show enhanced libido and sexual prowess among all test subjects to some varying degree. When the dosage is increased negative effects seem to start occurring and sometimes if the chemical is being given at unregulated times then it does not matter how big or small the dosage is, there would negative side effects like muscle tension, headache, nausea, and anxiety. Due to the less testing done on this research chemical there is little to none precedents where the toxicity and its addictive properties have been recorded which is why you should always use harm reduction practices while using this narcotic chemical.
The psychedelic effects of this chemical are believed to be coming from the 5-HT2A receptor which acts as a partial agonist. There are other contributing factors like the inhibition of MAO (digestive enzymes in our stomach) but there is no certainty behind these determinations which is why extreme caution is needed whenever tests are being run. The duration of “flow state” induced by this research chemical is supposed to last from 5-8 hours depending on how big the dosage is; Regular low amount of dosage with carefully calculated time gap is essential to see any fruitful results which is why most researchers would suggest a normal rest period of 3-4 days.
The region of the brain affected by this chemical is supposed to contribute in almost every single thing that happens in or to our body which is why to fully understand the effects careful and extensive research is required showing variant factors of our body being affected our different time periods. Things like sensory perception, behaviour modification, better tactile responding stimulus and so many more things are being currently cross-examined when the brain is being affected by this substance. This is all possible because how strongly 5-MeO-MiPT relates to the structure of serotonin itself which is why the receptors in our brain like 5-HT1A, 5-HT1B, 5-HT2A get easily affected by this research chemical. This causes disruption in our neurotransmitters in the brain and makes all the control loops collapse by being overwhelmed by stimulus at such a large scale. lizard labs have mpt tryptamine and you can order it in the form of 4-ho-mipt pellets, as they are the largest wholesale research chemicals usa provider meaning they have everything you need like 1plsd, 2fdka and much more.
5-MeO-MiPT can be taken orally, or it can be smoked using the predetermined methods. Depending on how you are taking this research chemical the different parts of our brain are affected due to the different pathways it takes to our brain. Our liver which is known to remove most of the toxicity lessens the effect and hence the states induced by the patients are somewhat similar to a less prominent dosage taken by smoke. Lizard labs have everything you need like the whole 5 meo mipt shop to test out the varying type of doses.
There are two phases of this substance that we can break the whole experience into which are reported by the habitual use of a regulated time period, the tests done were performed on experienced patients and that is the reason they were able to report everything with such high detail and intensity. The first half of the experience is reported to be stimulating and entactogenic, which basically means that the research chemical starts affecting our sense of touch and slowly moves up the other senses. It also means that the emotional part of our brain also starts flooding with hormones and it makes the test subjects much more susceptible to an emotional behaviour rut. The second half is similar to the most affects caused by any other tryptamine class of psychedelic meaning common effects like time distortions, visions, numbing of senses (some or none), emotional fits depending on the state of mind the patient is in and many other reported effects.
The reported chemical is supposed to be taken with extreme care and if the patient is inexperienced then it is strongly advised to be given the chemical orally with really small dosages ranging from 10-20 micrograms so that patient has a present state of mind where he can remember all the things he is experiencing after the “flow state” ends. Flow state can also be induced easily by keeping the dosage low and if repeated there should be a time gap of a week, you can change the dosage but it can lead patients entirely skipping the flow state and start showing adverse effects of the said research chemical.